Ahmed El-Sohemy
Ahmed El-SohemyPhD
Professor
Department of Nutritional Sciences

Contact Info

T. (416) 946-5776
F. (416) 978-5882

Location

FitzGerald Building, Room 350
150 College Street
Toronto
ON, M5S 3E2

Research Interests

Research program in nutrigenomics and nutrigenetics aims to understand how genetic and dietary factors interact to regulate various metabolic and biochemical pathways involved in the development of cardiometabolic disease as well as athletic performance.

Accepting

Not accepting new students

Research/Teaching

Research Synopsis:

The overall goal of my research program in nutrigenomics and nutrigenetics is to identify biomarkers of dietary exposure and elucidate the genetic basis for variability in nutrient response and dietary preferences. Our research program employs metabolomics, proteomics, and genomics to study the effects of diet on human health. This approach will help us to understand how genetic and dietary factors interact to regulate various metabolic and biochemical pathways involved in the development of chronic diseases. We have also been studying the effects of disclosing genetic information on eating behaviours along with exploring attitudes and perceptions of genetic testing. Other research projects focus on micronutrient genomics, genetics of caffeine response, and genetic determinants of eating habits as well as athletic performance.       

Publications and Awards

Recent Publications

Jamnik, J., García-Bailo, B., Borchers, H.C. and El-Sohemy, A. (2015) Gluten intake is associated with plasma α2-macroglobulin in young adults without celiac disease. J. Nutrition. 145(6):1256-62.

Dias, A.G., Eny, K.M., Cockburn, M., Chiu, W., Nielsen, D.E., Duizer, L., and El-Sohemy, A. (2015) Variation in the TAS1R2 gene, sweet taste perception and intake of sugars. J. Nutrigenetics Nutrigenomics.

Nielsen, D.E. and El-Sohemy, A. (2014) Disclosure of Genetic Information and Change in Dietary Intake: A Randomized Controlled Trial. PLoS One 9: e112665.

Nielsen, D.E. and El-Sohemy, A. (2014) Perceptions of genetic testing for personalized nutrition: a randomized trial of DNA-based dietary advice. J. Nutrigenetics Nutrigenomics. 7(2):94-104.

Wang, J., García-Bailo, B., Nielsen, D.E. and El-Sohemy, A. (2014) ABO Genotype, 'Blood-Type' Diet and Cardiometabolic Risk Factors. PLoS One 9: e84749.

Tian, O., Josse, A.R., Borchers, C.H. and El-Sohemy, A. (2013) Association Between Caffeine Intake and the Plasma Proteome in Humans. Journal of Caffeine Research. 3(4):175-81.

García-Bailo, B., J. Jamnik, L.A. Da Costa, A. Badawi, and El-Sohemy, A. (2013) Genetic variation in the vitamin D receptor and biomarkers of cardiometabolic disease in an ethnically diverse population of young adults. J Nutrigenetics Nutrigenomics 6:256-67.

García-Bailo, B., Jamnik, J., Da Costa, L.A., Borchers, C.H., Badawi, A., El-Sohemy, A. (2013) Plasma 25-Hydroxyvitamin D, Hormonal Contraceptive Use, and the Plasma Proteome in Caucasian, East Asian, and South Asian Young Adults. J. Proteome Res. 12:1797-1807.

Dias, A., Rousseau, D., Duizer, L., Cockburn, M., Chiu, M., Nielsen, D. and El-Sohemy, A. (2013) Genetic Variation in Putative Salt Taste Receptors and Salt Taste Perception in Humans. Chem Senses. 38:137-45.

Nielsen D.E., El-Sohemy, A. (2012) Applying genomics to nutrition and lifestyle modification. Personalized Medicine. 9(7):739-749.

Josse, A.R., Da Costa, L.A., Campos, H. and El-Sohemy, A. (2012) Associations between polymorphisms in the AHR gene and CYP1A1-CYP1A2 gene region and habitual caffeine consumption. Am. J. Clin. Nutr. 96:665-71.

Mauer, L. and El-Sohemy, A. (2012) Prevalence of cilantro (Coriandrum sativum) disliking among different ethnocultural groups. Flavour 1:8.

Fischer K, Da Costa LA, García-Bailo B, Borchers CH, and El-Sohemy, A. (2012) Glutathione S-Transferase (GST) M1, but Not GSTT1, Genotype Influences Plasma Proteomic Profiles in Caucasian and East Asian Young Adults. J Proteome Res. 11:5022-33.

Nielsen, D.E. and El-Sohemy, A. (2012) A randomized trial of genetic information for personalized nutrition. Genes Nutr.7:559-66.

Cahill, L., and El-Sohemy, A. (2010) Haptoglobin genotype modifies the association between dietary vitamin C and serum ascorbic acid deficiency. Am. J. Clin. Nutr. 92:1494-500.

Eny, K.M, Wolever, T.M.S., Corey, P.N. and El-Sohemy, A. (2010) Genetic variation in TAS1R2 (Ile191Val) is associated with consumption of sugars in overweight and obese individuals in two distinct populations. Am. J. Clin. Nutr. 92:1501-10.

Eny, K., Cory, P. and El-Sohemy, A. (2009) Dopamine D2 receptor genotype (C957T) is associated with habitual sugar consumption in a free-living population. J. Nutrigenetics Nutrigenomics 2: 235-242.

Cahill, L., Fontaine-Bisson, B. and El-Sohemy, A. (2009) Functional genetic variant of glutathione S-transferase protects against ascorbic acid deficiency. Am. J. Clin. Nutr. 90:1411-17.

Cahill, L., and El-Sohemy, A. (2009) Vitamin C transporter gene polymorphisms, dietary vitamin C and serum ascorbic acid. J. Nutrigenetics Nutrigenomics. 2: 292-301.

Cahill, L., Cory, P. and El-Sohemy, A. (2009) Vitamin C deficiency in a population of young Canadian adults. Am. J. Epidemiol. 170: 464-71.

Fontaine-Bisson, B., Wolever, T.M.S., Connelly, P.W., Corey, P.N. and El-Sohemy, A. (2009) NF-κB -94Ins/Del ATTG polymorphism modifies the association between dietary polyunsaturated fatty acids and HDL-cholesterol in two distinct populations. Atherosclerosis 204: 465-470.

Ozsungur, S., Brenner, D.M. and El-Sohemy, A. (2009) Fourteen well described caffeine withdrawal symptoms factor into three clusters. Psychopharmacology. 201: 541-48.

Garcia-Bailo, B., Toguri, C., Eny, K.M. and El-Sohemy, A. (2009) Genetic variation in taste and its influence on food selection. OMICS: Journal of Integrative Biology. 13: 69-80.
 

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