Research InterestsNutrition and gastrointestinal disorders.
Johane P. Allard is a professor of medicine at the University of Toronto, Canada, and is cross-appointed with the Department of Nutritional Sciences. She trained in gastroenterology at McGill University before completing a research fellowship, funded by the National Institute of Nutrition, at the University of Toronto.
2005 Editorial Board, Canadian Journal of Gastroenterology
2004-07 Editor, Lecture Series in Clinical Nutrition on CD-ROM
2003-04 Editor, Canadian Society for Clinical Nutrition Newsletter & Journal Review
2001 Editorial Reviewer, Journal of Geriatric Care
2001-04 Editor, Clinical Nutrition Rounds
1996-2000 Co-Editor, Current Opinion in Clinical Nutrition and Metabolic Care
Professional and Honorary Societies
2005 Member, Dr. F. M. Hill Advisory Board Trust Fund, Women’s College
Member, Crohn’s and Colitis Foundation of Canada
Member, Canadian Liver Foundation
Member, American College of Gastroenterology
2002-04 Director, Governing Board, Canadian Digestive Diseases Foundation
2001-04 Founder & President, Canadian Society for Clinical Nutrition
1997 Société francophone de nutrition parentérale et entérale
1994-96 Advisory Committee, Speciality Food Shop, Hospital for Sick Children
1994 Scientific Advisory Council, National Institute of Nutrition
1993-96 The Medicine Group (Canada) Limited
1991 Scientific Board, National Institutes of Health (NIH)
American Gastroenterological Association (AGA)
Canadian Association of Gastroenterology (CAG)
Ontario and Canadian Medical Associations (OCMA)
American Society of Clinical Nutrition (ASCN)
1991-96 Advisory Board, Clintec & Ross
1990 American Society of Parenteral and Enteral Nutrition (ASPEN)
1990-2001 American College of Nutrition (ACN)
Grant Review Committees
2006 Canadian Foundation for AIDS Research
2000 National Institute of Health
2001-04 Canadian Association of Gastroenterology
1996-99 Crohn’s and Colitis Foundation of Canada
2010 Advisory Board, Canadian Nutrition Society
2009 Chair, Canadian Malnutrition Task Force
2008 Vice-Chair, GI Examination Board Royal College of Physicians and Surgeons of Canada
2006 Member, GI Examination Board, Royal College of Physician and Surgeons of Canada
2005 Chair, Canadian Home Total Parenteral Nutrition Registry
2000-10 Advisory Board, Canadian Society for Clinical Nutrition
1996-99 Crohn’s and Colitis Foundation of Canada
2006 Department Division Director Committee, University of Toronto
2005 Faculty Development Committee
2005-07 Chair, Gender Issues Committee, Medicine, University of Toronto
2003-07 Gender Issues Committee, Medicine, University of Toronto
1999-2001 Search Committee for Chief of Gastro-intestinal Diseases, UHN Toronto
1994-96 Faculty Advisory Committee on Animal Services, University of Toronto
1985-86 Training Committee, McGill University, Montreal
1982-83 Intensive Care Unit of Teaching Committee, Maisonneuve-Rosemont Hospital, Montreal
Executive Board, Maisonneuve‑Rosemont Hospital, Montreal
2002 Member, Senior Advisory Committee, UHN
Member, Economics Committee, UHN
1998 Member, Awards Committee, Institute of Medical Science, U of T
1990 Director, the Nutrition Program, Toronto General Hospital
Chair, the Nutrition Review Committee
2002-07 Chair, Women’s Issues Committee, UHN/MSH
1995-97 Section Chief, Luminal Division, Toronto Hospital
1994-99 Toronto Hospital Economics Committee
1994-97 GI Training Program Committee
Pharmaceutics and Therapeutics Committee
1989-90 Nutrition Committee, Toronto Hospital
Gut microbiome in bariatric care
Many people who are severely obese have high blood sugar levels and type 2 diabetes. Both obesity and type 2 diabetes are growing health problems in Canada. The only reliable and effective treatment for severe obesity is weight loss surgery, which also remarkably improves type 2 diabetes and blood sugar control, even before weight loss occurs. New studies show that changes in the gut bacteria can play an important role in this process. The purpose of this project is to examine the gut bacteria of patients undergoing bariatric surgery in order to clarify their role in improvements of blood sugar control.
Non-alcoholic fatty liver disease and nutrition-related factors that could contribute to the pathogenesis, including:
- Diet and lifestyle (dietary intake, obesity, physical activity)
- Oxidative stress and antioxidants
- Lipid profile of liver and other tissues (lipid classes, fatty acid composition)
- Hepatic gene expression (genes related to oxidative stress, lipid metabolism, insulin resistance)
- Intestinal microbiota
Home Parenteral Nutrition
Dr. Allard's team is managing the Canadian Home Total Parenteral Nutrition (TPN) Registry, which collects demographic information, medical history, and health status of patients in Home TPN programs across Canada. Dr. Allard’s team is also conducting a multicentre, randomized, controlled trial to examine the effects of fish-oil based lipid emulsion on parenteral nutrition-associated liver disease. Dr. Allard's areas of expertise also include inflammatory bowel disease, celiac disease, and short bowel syndrome. In addition, she and her team have conducted studies on patients with HIV infection or chronic Hepatitis C infection, as well as lung and liver transplant patients.
Nutrition Care in Canadian Hospitals
Dr Allard is one of the co-chairs of the recently founded Canadian Malnutrition Task Force (http://nutritioncareinca>nada.ca/). The aim of the task force is to create a knowledge base and close the gaps between research and practice in the prevention, detection, and treatment of malnutrition in Canadians through the continuum of care. Their first study ‘Nutrition Care in Canadian Hospitals’ is currently conducted at multiple hospitals across Canada, including the University Health Network with Dr. Allard as a site investigator. Dr. Allard's areas of expertise also include inflammatory bowel disease, celiac disease, and short bowel syndrome. In addition, she and her team have conducted studies on patients with HIV infection or chronic hepatitis C infection, as well as lung and liver transplant patients.
Recent Theses/Graduate Projects Supervised
Publications and Awards
Arendt BM, Comelli EM, Ma DW, Lou W, Teterina A, Kim T, Fung SK, Wong DK, McGilvray I, Fischer SE, Allard JP. Altered hepatic gene expression in non-alcoholic fatty liver disease is associated with lower hepatic n-3 and n-6 polyunsaturated fatty acids. Hepatology. 2015 Jan 10. doi: 10.1002/hep.27695. [Epub ahead of print]
Allard JP, Keller H, Jeejeebhoy KN, Laporte M, Duerksen D, Gramlich L, Payette H, Bernier P, Vesnaver E, Davidson B, Teterina A, Lou W. Malnutrition at hospital admission: contributors and impact on length of stay. A prospective cohort study from the Canadian Malnutrition Task Force. JPEN J Parenter Enteral Nutr. 2015 Jan 26. pii: 0148607114567902. [Epub ahead of print].
Allard JP, Keller H, Jeejeebhoy KN, Laporte M, Duerksen D, Gramlich L, Payette H, Bernier P, Davidson B, Teterina A, Lou W. Decline in nutritional status is associated with prolonged length of stay in hospitalized patients admitted for 7 days or more: a prospective cohort study. Clin Nutr. 2015 Jan 21 doi: 10.1016/j.clnu.2015.01.009. [Epub ahead of print]
Duerksen DR, Keller HH, Vesnaver E, Laporte M, Jeejeebhoy KN, Payetter H, Gramlich L, Bernier P, Allard JP. Nurses' perceptions regarding the prevalence, detection and causes of malnutrition in Canadian hospitals: results of a Canadian Malnutrition Task Force Survey. JPEN J Parenter Enteral Nutr. 2014 Sep 4. pii: 0148607114548227. [Epub ahead of print]
Keller H, Allard JP, Laporte M, Davidson B, Payette H, Bernier P, Jeejeebhoy K, Duerksen DR, Gramlich L. Predictors of dietitian consult on medical and surgical wards. Clin Nutr. 2014 Nov 29. pii: S0261-5614(14)00292-1. doi: 10.1016/j.clnu.2014.11.011. [Epub ahead of print].
Mouzaki M, Comelli EM, Arendt BM, Bonengel J, Fung SK, Fischer S, McGilvray ID, Allard JP. Intestinal Microbiota in Patients with Non-Alcoholic Fatty Liver Disease. Hepatology 2013 Jul; 58(1):120-7. doi: 10.1002/hep.26319. [Epub 2013 May 14].
Da Silva H, Arendt BM, Noureldin SA, Therapondos G, Guindi M, Allard JP. A Cross-Sectional Study Assessing Dietary Intake and Physical Activity in Canadian Patients with Non-Alcoholic Fatty Liver Disease versus Healthy Controls. J Acad Nutr Diet. 2014; 114(8):1181-1194. pii: S2212-2672(14)00099-9. doi: 10.1016/j.jand.2014.01.009. [Epub 2014 Mar 14]
Schwenger KJP, Allard JP. Clinical approaches to non-alcoholic fatty liver disease. (Review) World J Gastroenterol. 2014 Feb; 20(7):1712–23. doi: 10.3748/wjg.v20.i7.1712.
Duerksen DR, Keller HH, Vesnaver E, Allard JP, Bernier P, Gramlich L, Payette H, Laporte M, Jeejeebhoy K. Physicians' Perceptions Regarding the Detection and Management of Malnutrition in Canadian Hospitals: Results of a Canadian Malnutrition Task Force Survey. JPEN J Parenter Enteral Nutr. 2014 Jun 2. pii: 0148607114534731. [Epub ahead of print]
O'Keefe SJ, Jeppesen PB, Gilroy R, Pertkiewicz M, Allard JP, Messing B. Safety and Efficacy of Teduglutide After 52 Weeks of Treatment in Patients with Short Bowel Syndrome Intestinal Failure. Clin Gastroenterol Hepatol. 2013 Jul; 11(7):815-23.e1-3. doi: 10.1016/j.cgh.2012.12.029. [Epub 2013 Jan 17]
Arendt BM, Ma DWL, Simons B, Noureldin S, Therapondos G, Guindi M, Sherman M, Allard JP. Non-alcoholic fatty liver disease is associated with lower hepatic and erythrocyte ratios of phosphatidylcholine to phosphatidylethanolamine. Appl Physiol Nutr Metabolism 2013 Mar; 38(3):334-40. doi: 10.1139/apnm-2012-0261. [Epub 2012 Oct 15].
Fernandes G, Kaila B, Jeejeebhoy K, Gramlich LM, Armstrong D, Allard JP. Canadian Home Total Parenteral Nutrition (HTPN) Registry: Validation and Patient Outcomes. JPEN 2012; 36(4):407-14. doi: 10.1177/0148607111434599 [Epub 2012 Feb 10].
Mouzaki M, Allard J. Non-alcoholic steatohepatitis: the therapeutic challenge of a global epidemic. Ann Gastroenterol. 2012; 25(2): 207-217.
Honours and Awards
2010 Supervised PhD Student, Arcand JoAnne – Nestle Nutrition Graduate Student Award
2003 Best Abstract Award, Canadian Society for Clinical Nutrition 2003
1993 Best Paper, National Colon-Proctology Meeting, Brazil (Supervised recipient Helio Plapler)
1997 Best Paper, CAG Fellowship course (Supervised recipient Helena Lau)
1995 ASPEN: Harry Vars Award (Supervised recipient Albert Verhage)
1990-91 Outstanding Clinical Teacher Award (Joint Undergraduate Medicine & Surgery Education Committee),
the Toronto Hospital
1990 Dean’s Fund
1986-89 National Institute of Nutrition Fellowship Award