Research InterestsRole of dietary factors and susceptibility genes in cancer development.
AcceptingNot accepting new students
Publications and Awards
Archer, M.C. Role of Sp transcription factors in the regulation of cancer cell metabolism. Genes and Cancer, 2, 712-719, 2011.
Li, Y-J., Liu, G., Li, Y., Vecchiarelli-Federico, L.M., Liu, J.C., Zacksenhaus, E., Shan, S.W., Yang, B.B., Li, Q., Dash, R., Fisher, P.B., Ben-David, Y. and Archer, M.C. mda-7/IL-24 expression inhibits breast cancer through up-regulation of growth arrest-specific gene 3 (gas3) and disruption of β1 integrin function. Mol. Cancer Res., 11, 593-603, 2013.
Hopperton, K.E., Duncan, R.E., Bazinet, R.P., and Archer, M.C. Fatty acid synthase plays a role in cancer metabolism beyond providing fatty acids for phospholipid synthesis or sustaining elevations in glycolytic activity. Exp. Cell Res., 320, 302-310, 2014.
Menezes, M., Shen, X-N., Das, S., Emdad, L., Guo, C., Yuan, F., Li, Y-J., Archer, M.C., Zacksenhaus, E., Windle, J., Subler, M., Ben-David, Y., Sarkar, D., Wang, X-Y. and Fisher, P.B. MDA-7/IL-24 functions as a tumor suppressor gene in vivo in transgenic models of breast cancer. Oncotarget, 6, 36928-42, 2015.
Li, Y-J., Liu, G., Xia, L., Xiao, X., Liu, J.C., Menezes, M.E., Das, S.K., Emdad, L., Sarkar, D., Fisher, P.B., Archer, M.C., Zacksenhaus, E. and Ben-David, Y. Suppression of Her2/Neu mammary tumor development in mda-7/IL-24 transgenic mice. Oncotarget, 6, 36943-54, 2015.
Yang, K., Fard, S., Furrer, R., Archer, M.C., Bruce, W.R., Lip, H.Y., Mehta, R., O’Brien, P.J., Giacca, A., and Ward, W.E. Risk factors for colorectal cancer in man induce aberrant crypt foci in rats: preliminary findings. Nutrition and Cancer, 68, 94-104, 2016.
Honours and Awards
1994-04 Natural Sciences and Engineering Research Council Research Chair in Nutritional Toxicology
1974 Future Leader Award, International Life Sciences Institute (ILSI)
1977-82 National Institutes of Health Research Career Development Award
1977 Fellow of the Royal Society of Chemistry (London)