Research InterestsDietary fiber and chronic disease; Rheology vs. physiology of soluble dietary fibre; Prevention and management of the heart disease risk factors; Epidemiology of heart disease in ethnic groups
Dr. Vlad Vuksan holds a dual professorship in the Faculty of Medicine and the Department of Nutritional Sciences at the University of Toronto. He has made significant contributions, within a unique multidisciplinary clinical research group, investigating the physiological effects of food.
He joined St. Michael's Hospital in 1986, where he developed a highly effective viscous fibre blend, demonstrated the significant role of ginseng when applied in nutraceuticals, and used Salvia hispanica alba (chia) wholegrain in reducing blood glucose, blood pressure, body inflammation, and fibrinolysis. Based on the findings of his work, he is supported by major health agencies, agriculture organizations, local, and international industries. Several industries were able to develop a number of successful, new commercial food products.
Dr. Vuksan's pursuits are at times pioneering within the field of nutrition, medicinal herbs, food science, and technology. Aside from his teaching duties, his mandate is to continue his clinical and epidemiological research in the field of nutrition, human health, and heart disease. He is a member of numerous professional associations and has achieved international recognition as is reflected in the numerous invitations he receives to participate in international meetings.
Focused on the development of novel therapies for modifiable, conventional, and emerging risk factors for diabetes mellitus, cardiovascular disease, and those featuring the metabolic syndrome.
Publications and Awards
Vuksan V, Whitham D, Sievenpiper JL, Jenkins AL, Rogovik AL, Bazinet RP, Vidgen E, Hanna A. Supplementation of Conventional Therapy with the Novel Grain Salba (Salvia hispanica L.) Improves Major and Emerging Cardiovascular Risk Factors in Type 2 Diabetes: Results of a Randomized Controlled Trial. Diabetes Care. 2007 Aug 8: 1-15 (in press).
Panahi S, Ezatagha A, Temelli F, Vasanthan T, Vuksan V. b-Glucan from two Sources of Oat Concentrates Affect Postpradnial Glycemia in Relation to the Level of Viscosity. J of Amer Coll of Nutr 2007 (in Press).
Dascalu A, Sivenpiper JL, Jenkins AL, Stavro MP, Arnason JT, Vuksan V. Five Batches of Ontario Grown American Ginseng (Panax quinquefolium) Root Produce Comparable Reductions of Postprandial Glycemia in Healthy Individuals. CJPP, 2007 (in Press).
Sievenpiper JL, Ezatagha A, Dascalu A, Vuksan V. When a placebo is not a 'placebo': a placebo effect on postprandial glycaemia. Br J Clin Pharmacol. 2007 May 17.
Razak F, Anand SS, Shannon H, Vuksan V, Davis B, Jacobs R, Teo KK, McQueen M, Yusuf S. Defining obesity cut points in a multiethnic population. Circulation. 2007 Apr 24; 115(16):2111-8.
Merchant AT, Anand SS, Kelemen LE, Vuksan V, Jacobs R, Davis B, Teo K, Yusuf S; SHARE and SHARE-AP Investigators. Carbohydrate intake and HDL in a multiethnic population. Am J Clin Nutr. 2007 Jan; 85(1):225-30.
Anand SS, Razak F, Davis AD, Jacobs R, Vuksan V, Teo K, Yusuf S. Social disadvantage and cardiovascular disease: development of an index and analysis of age, sex, and ethnicity effects. Int J Epidemiol. 2006 Oct; 35(5):1239-45.
Vuksan V, Sung MK, Sievenpiper JL, Stavro PM, Jenkins AL, Di Buono M, Lee KS, Leiter LA, Nam KY, Arnason JT, Choi M, Naeem A. Korean red ginseng (Panax ginseng) improves glucose and insulin regulation in well-controlled, type 2 diabetes: Results of a randomized, double-blind, placebo-controlled study of efficacy and safety. Nutr Metab Cardiovasc Dis. 2006 Jul 21.
Sievenpiper JL, Sung MK, Di Buono M, Seung-Lee K, Nam KY, Arnason JT, Leiter LA, Vuksan V. Korean red ginseng rootlets decrease acute postprandial glycemia: results from sequential preparation- and dose-finding studies. J Am Coll Nutr. 2006, Apr; 25(2): 100-7.
P. Mark Stavro; Minna Woo; Tibor F. Heim., John L. Sievenpiper; Lawrence A. Leiter, Vladimir Vuksan. Long-term Intake of North American Ginseng is Associated with a Neutral Effect on 24-Hour Blood Pressure and Renal Function. A Randomized, Controlled, Trial in Hypertensive Individuals, Hypertension, 2006, 47: 791-6.
Stavro M, Woo M, Heim T, Leiter L, Vuksan V. North American Ginseng Exerts a Neutral Effect on Blood Pressure in Individuals with Hypertension. Hypertension 2005, Aug; 46(2):406-11.
Merchant AT, Anand SS, Vuksan V, Jacobs R, Davis B, Teo K, Yusuf S. Protein intake is inversely associated with abdominal obesity in a multi-ethnic population. J Nutr. 2005, 135 (5):1196-201.
Vuksan V, Sievenpiper JL. Herbal remedies in the management of diabetes: lessons learned from the study of ginseng. Nutr Metab Cardiovasc Dis. 2005 Jun;15(3):149-60.
Razak F, Anand S, Vuksan V, Davis B, Jacobs R, Teo KK, Yusuf S. Ethnic differences in the relationship between obesity and glucose metabolic abnormalities: a cross-sectional population-based study. Int J Obes Metab Disor. 2005 Mar 22.