Profile

 

John L Sievenpiper, MD, PhD, FRCPC
Associate Professor, Department of Nutritional Sciences
Scientist, Li Ka Shing Knowledge Institute, St. Michael's Hospital
Knowledge Synthesis Lead, Toronto 3D Knowledge Synthesis & Clinical Trials Unit, St. Michael's Hospital
Consultant Physician, Division of Endocrinology and Metabolism, Department of Medicine, St. Michael's Hospital

P: +1 416 867 7475
john.sievenpiper@utoronto.ca


Primary Affiliations:

  • Associate Professor, Department of Nutritional Sciences

Other Affiliations:

  • Scientist, Li Ka Shing Knowledge Institute, St. Michael's Hospital
  • Knowledge Synthesis Lead, Toronto 3D Knowledge Synthesis & Clinical Trials Unit, Clinical Nutrition and Risk Factor Modification Centre, St. Michael's Hospital, St. Michael's Hospital
  • Consultant Physician, Division of Endocrinology and Metabolism, Department of Medicine, St. Michael's Hospital

Committee Appointments:

  • Executive board member, Diabetes Nutrition Study Group of the European Association for the Study of Diabetes
  • Co-chair, 33rd International Symposium on Diabetes and Nutrition, Toronto, ON, Canada, June 9-12, 2015
  • Scientific Advisor, Carbohydrate Committee, International Life Science Institute North America
  • Scientific Advisor, Food, Nutrition, and Safety Panel (FNSP), International Life Science Institute North America
  • Expert Committee member, Canadian Diabetes Association 2013 Clinical Practice Guidelines for Nutrition therapy
  • Expert Committee member, European Association for the Study of Diabetes 2015 Clinical Practice Guidelines for Nutrition therapy
  • Expert Committee Member, Transcultural Diabetes & Nutrition Algorithm

Editorial Appointments:

  • Editorial Board Member, American Journal of Clinical Nutrition
  • Editorial Board Member, Nutrients
  • Associate Editor, Frontiers in Nutrition - Nutrition Methodology

Education/Degrees:

  • FRCPC, Medical Biochemistry, McMaster University
  • MD, St. Matthew's University School of Medicine
  • Postdoctoral Fellowship, Nutritional Sciences, University of Toronto
  • PhD, Nutritional Sciences, University of Toronto
  • MSc, Nutritional Sciences, University of Toronto

Awards and recognition:

  • PSI Foundation Graham Farquharson Knowledge Translation Fellowship

Professional Memberships:

  • Canadian Diabetes Association
  • American Society of Nutrition
  • Canadian Association of Medical Biochemists
  • Diabetes and Nutrition Study Group of the European Association for the Study of Diabetes

Research:

  • My research program strives to identify and investigate important diet and disease questions in relation to diabetes and cardiovascular diseases with the view to informing clinical practice guidelines, public health policy, and the design of future randomized controlled trials. Clinical practice guidelines and public health policy are moving away from traditional nutrient-centric dietary approaches to more food and dietary pattern-based approaches, a process I helped initiate and steer in the Canadian Diabetes Association 2013 Clinical Practice Guidelines for Nutrition Therapy. Through randomized controlled trials, knowledge syntheses (systematic reviews and meta-analyses), and knowledge translation activities, my research program has attempted to be a driver of this modernization investigating the role of dietary sugars, legumes/pulses, tree nuts, and comprehensive dietary patterns in cardiometabolic risk.

Current students:

  • Effie Viguiliouk (MSc)
  • Vivian Choo (MSc)
  • Jarvis Noronha (undergraduate research project)
  • Catherine Braunstein (undergraduate research project))

Recent publications:


  • Chiavaroli L, Ha V, de Souza RJ, Kendall CWC, Sievenpiper JL. Overstated associations between fructose and non-alcoholic fatty liver. J Pediatr Gastroenterol Nutr. 2015 Jan 5. [Epub ahead of print]

  • Chiavaroli L, Ha V, de Souza RJ, Kendall CWC, Sievenpiper JL. Uninterpretable results from a meta-analysis of fructose and metabolic syndrome. Nutrition 2015;31:419-20.

  • Wolever TMS, Sievenpiper JL. Revised Food Labeling in North America: the Blind Leading the Blind? Eur J Clin Nutr. 2014;68:1275-6

  • Kahn R, Sievenpiper JL. Dietary Sugar and Body Weight: Have we reached a crisis in the epidemic of obesity and diabetes? We have, but the pox on sugar is overwrought and overworked. Diabetes Care 2014;37:957-62

  • Ha V, Chiavaroli L, de Souza RJ, Kendall CWC, Sievenpiper JL. Differential association of sugar-sweetened beverages (SSBs) in men and women: is it the sugar or calories? Am J Clin Nutr. 2014;100:1399-400

  • Chiavaroli L, Ha V, de Souza RJ, Kendall CWC, Sievenpiper JL. Fructose in obesity and cognitive decline: Is it the fructose or the excess energy? Nutr J 2014;13:27.

  • Chiavaroli L, Ha V, Kendall CWC, Sievenpiper JL. Is industrial fructose just a marker of an unhealthy dietary pattern J Hepatol. 2014;61:172-3.

  • Blanco Mejia S, Kendall CWC, Viguiliouk E, Augustin LS, Ha V, Cozma AI, Mirrahimi A, Maroleanu A, Chiavaroli L, Leiter LA, de Souza RJ, Jenkins DJA, Sievenpiper JL. Effect of tree nuts on metabolic syndrome criteria: A systematic review and meta-analysis of randomized controlled trials. BMJ Open. 2014;4:e004660

  • Viguiliouk E, Kendall CWC, Blanco-Mejia S, Cozma AI, Ha V, Mirrahimi M, Jayalath VH, Augustin LS, Chiavaroli L, Leiter LA, de Souza RJ, Jenkins DJA, Sievenpiper JL. The Effect of Tree Nuts on Glycemic Control: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. PLoS One. 2014;9:e103376

  • Li SS, Kendall CWC, de Souza RJ, Jayalath VH, Cozma AI, Ha V, Mirrahimi A, Chiavaroli L, Augustin L, Blanco Mejia S, Leiter LA, Beyene J, Jenkins DJA, Sievenpiper JL. Dietary Pulses, Satiety, and Food Intake: A Systematic Review and Meta-Analysis of Acute Feeding Trials. Intl J Obesity Obesity (Silver Spring). 2014;22:1773-80

  • Brisbois TD, Marsden SL, Anderson GH, Sievenpiper JL. Estimated intakes and sources of total and added sugars in the Canadian diet. Nutrients. 2014;6:1899-912

  • Ha V, Chiavaroli L, de Souza RJ, Kendall CWC, Sievenpiper JL. Low sodium but not low fructose improves mtDNA. Exp Clin Endocrinol Diabetes 2014;122:379-80

  • International Carbohydrate Quality Consortium (ICQC). Glycaemic index: did Health Canada get it wrong? Br J Nutr 2014;111:380-2.

  • Chiavaroli L, Mirrahimi A, de Souza RJ, Sievenpiper JL. Meta-Analysis of Fructose and Cholesterol: A Concern regarding Missing Data. J Nutr 2014;144:538-9

  • Mirrahimi A, Chiavaroli L, Srichaikul K, Augustin LS, Sievenpiper JL, Kendall CW, Jenkins DJ. The role of glycemic index and glycemic load in cardiovascular disease and its risk factors: a review of the recent literature. Curr Atheroscler Rep. 2014;16:381.

  • Sievenpiper JL, de Souza RJ, Cozma AI, Chiavaroli C, Ha V, Mirrahimi A. Fructose vs. glucose and metabolism: do the metabolic differences matter? Curr Opin Lipidol. 2014;25:8-19.

  • Ha V, Sievenpiper JL, de Souza RJ, Jayalath VH, Mirrahimi A, Chiavaroli L, Di Buono M, Bernstein AM, Leiter LA , Kris-Etherton PM, Vuksan V, Beyene J, Kendall CWC, Jenkins DJA. The Effect of Dietary Pulses on Established Lipid Therapeutic Targets of Cardiovascular Disease: A Systematic Review and Meta-Analysis of controlled feeding trials, CMAJ. 2014;186:E252-62

  • Jayalath VH, Sievenpiper JL, de Souza RJ, Ha V, Mirrahimi A, Santaren ID, Blanco Mejia S, DiBuono M, Jenkins AL, Leiter LA, Wolever TWS, Beyene J, Kendall CWC, Jenkins DJA. Relation of fructose-containing sugar consumption with risk of hypertension: A systematic review and meta-analysis of prospective cohorts. J Am Coll Nutr 2014;33:328-39

  • Jenkins DJ, Kendall CW, Vuksan V, Faulkner D, Augustin LS, Mitchell S, Ireland C, Srichaikul K, Mirrahimi A, Chiavaroli L, Blanco Mejia S, Nishi S, Sahye-Pudaruth S, Patel D, Bashyam B, Vidgen E, de Souza RJ, Sievenpiper JL, Coveney J, Josse RG, Leiter LA. Effect of Lowering the Glycemic Load With Canola Oil on Glycemic Control and Cardiovascular Risk Factors: A Randomized Controlled Trial. Diabetes Care. 2014;37:1806-14

  • Chiu S, Sievenpiper JL, de Souza RJ, Cozma AI, Mirrahimi A, Carleton AJ, DiBuono M, Jenkins AL, Leiter LA, Wolever TWS, Don Wauchope AC, Beyene J, Kendall CWC, Jenkins DJA Effect of fructose on non-alcoholic fatty liver disease (NAFLD): A Systematic Review and Meta-analysis of controlled feeding trials. Eur J Clin Nutr. 2014;68:416-23

  • Wang DD, Sievenpiper JL, de Souza RJ, Cozma AI, Ha V, Chiavaroli L, Mirrahimi A, Carleton AC, Beyene J, Kendall CWC, Jenkins DJA. Effect of Fructose on Postprandial Triglycerides: A Systematic Review and Meta-Analysis of Controlled Feeding Trials. Atherosclerosis 2014;232:125-133

  • Gougeon R, Sievenpiper JL, Jenkins D, Yale JF. Bell R, Després JP, Ransom TPP, Camelon K, Dupre J, Kendall C, Hegazi R, Marchetti A, Hamdy O, Mechanick, JI. Transcultural Diabetes Nutrition Algorithm (tDNA): A Canadian perspective. Int J Endocrinol. 2014;2014:151068.

  • Sievenpiper JL and Dworatzek PDN. Food and dietary pattern based recommendations: An emerging approach to clinical practice guidelines for nutrition therapy in diabetes. Canadian J Diabetes 2013;37:51-57.

  • Sievenpiper JL, de Souza RJ. Are sugar-sweetened beverages the whole story? Am J Clin Nutr. 2013;98:261-263

  • Dworatzek PDN, Arcudi K, Gougeon J, Husein N, Sievenpiper JL, Williams S. Nutrition Therapy. In Canadian Diabetes Association Clinical Practice Guidelines Expert Committee. Canadian Diabetes Association 2013 Clinical Practice Guidelines for the Prevention and Management of Diabetes in Canada. Can J Diabetes 2013; 37 (Suppl 1):S45-S55

  • Cozma AI, Sievenpiper JL. The Role of Fructose, Sucrose, and High-fructose Corn Syrup in Diabetes. U.S. Endocrinology 2013;9:128–38

  • Ha V, Jayalath VH, Cozma AI, Mirrahimi A, de Souza RJ, Sievenpiper JL. Fructose-containing sugars blood pressure and cardiometabolic risk: A critical review. Curr Hypertens Rep. 2013;15:281-97

  • PubMed

     

     


 

 

Address

St. Michael's Hospital
#6137-61 Queen Street East
Toronto, ON
M5C 2T2