Daniel Roth

Daniel Roth MD MSc PhD
Associate Professor — Status Only
Department of Nutritional Sciences
Daniel Roth
Contact Info
T: (416) 813-7654 ext 328807
F: (416) 813-6520
Hospital for Sick Children
555 University Avenue
Toronto, ON, M5G 1X8
Appointment Status Cross-Appointed
Accepting new students
2002 MD University of British Columbia
2003 MSc, Medical Science (Paediatrics), University of Alberta
2011 PhD, Human Nutrition, Department of International Health, The Johns Hopkins Bloomberg School of Public Health)

Daniel Roth received his MD in 2002 from the University of British Columbia. He completed a paediatric residency (2002-06) and MSc (2006) at the University of Alberta. In 2011, he earned a PhD in global public health and human nutrition at the Johns Hopkins Bloomberg School of Public. Dr. Roth is a clinician-scientist and assistant professor in the Division of Paediatric Medicine, Department of Paediatrics at the Hospital for Sick Children and University of Toronto. His research focuses on maternal and child health in low income settings.


Research Synopsis

Research Interests:

  • Global maternal-child health and nutrition
  • Nutrition-infection relationships
  • Vitamin D status during pregnancy and early infancy, with a particular focus on its determinants and consequences in South Asia
  • Application of pulse oximetry to the first-level management of sick young infants in developing countries
  • Calcium supplementation during pregnancy for the prevention of hypertensive diseases of pregnancy, preterm birth and neonatal mortality in resource-poor settings where dietary calcium intakes are low
  • Prevention, diagnosis and treatment of neonatal sepsis and infant lower respiratory tract infections in resource-limited settings

My current major research focus is to test the hypothesis that improvements in vitamin D status during pregnancy reduces the risk of adverse maternal-infant health outcomes in resource-poor settings. Our current clinical studies are ongoing in Dhaka, Bangladesh.

Publications and Awards

View PubMed search of this faculty member's recent publications.

Recent Publications

Roth DE: "Bones and beyond: an update on the role of vitamin D in child and adolescent health in Canada". Appl Physio Nutr Metab 2007: 32(4): 770-7.

Roth DE, Caufield L, Ezzati M, Black RE: "Acute lower respiratory infections in childhood: opportunities for reducing the global burden through nutritional interventions". Bull World Health Organ 2008: 86(5): 356-364.

Shamseer L, Roth DE, Tallet S, Hilliard R, Vohra S: A comparison of Canadian pediatric resident career plans in 1998 and 2006. Pediatrics 2008: 122(3): e1199-e120.

Roth DE, Jones AB, Prosser C, Robinson J, Vohra S: Vitamin D Receptor Polymorphins and the Risk of Acute Lower Respiratory Tract Infection in Early Childhood. J Inf Dis 2008: 197(5): 676-80.

Roth DE: "What should I say to parents about vitamin D supplementation from infancy to adolescence?" Padiatrics and Child Health 2009: 14(9): 575-7.

Roth DE, Jones AB, Prosser C, Robinson J, Vohra D: Vitamin D status is not associates with the risk of hospitalization for acute bronchiolitis in early childhood. Eur J Clin Nutr 2009: 63(2): 297-9.

Roth DE, Shah R, Black RE, Baqui A: Vitamin D status and acute lower respiratory infection in early childhood in Sylhet, Bangladesh. Acta Paediatrica 2010: 99(3): 389-93.

Roth DE, Richard SA, Black RE: Zinc for preventing acute lower respiratory infection in children: meta-analysis and meta -regression of randomized trials. Int J Epidemiol 2010: 39(3): 795-808.

Roth DE, Shah R, Black RE, Baqui A: Vitamin D status in Infancy in rural north-eastern Bangladesh: Preliminary observations and a review of potential determinants. Journal of Health, Population and Nutrition 2010: 28(5): 458-69.

Roth DE: Vitamin D supplementation during pregnancy: safety considerations in the design and interpretation of clinical trials. J Perinatol. 2011 Jul; 31(7): 449-59.

Roth DE, Mahmud A, Raqib R, Black RE, Baqui AH. Pharmacokinetics of a single oral dose of vitamin D3 (70,000 IU) in pregnant and non-pregnant women. Nutrition Journal 2012; 11:114.

Roth DE, Mahmud A, Raqib R, Akhtar E, Black RE, Baqui AH. Pharmacokinetics of high-dose weekly oral vitamin D3 supplementation during the third trimester of pregnancy in Dhaka, Bangladesh. Nutrients 2013; 5(3):788-810.

Roth DE, Mahmud A, Raqib R, Akhtar E, Perumal N, Pezzack B, Baqui AH. Randomized placebo-controlled trial of high-dose prenatal third-trimester vitamin D3 supplementation in Bangladesh: the AViDD trial. Nutrition Journal 2013; 12:47.

Roth DE, Perumal N, Al Mahmud A, Baqui AH. Maternal Vitamin D3 Supplementation during the Third Trimester of Pregnancy: Effects on Infant Growth in a Longitudinal Follow-Up Study in Bangladesh. J Pediatr. 2013 Aug 30.