The research in the Pausova lab is focused on early stages and trans-generational trajectories of common cardio-metabolic and brain diseases. It is guided by the following biomedical considerations: (1) many common cardio-metabolic and brain disease originate in utero; (2) they involve interactions between adverse environments and vulnerability genes; (3) many of these diseases emerge during adolescence and become established during middle-aged adulthood; and (4) most of them are multi-systemic, affecting both the brain and body.
The main research interests are:
Visceral adiposity and its links to cardiometabolic health, brain structure and cognition
Eating behavior, addiction and the adolescent brain
Genetic and environmental factors modulating DNA methylome