Williams Turpin
PhD
Qualification
- Research Associate, Program Manager, Mount Sinai Hospital (2024)
- Research Associate, University of Toronto, Mount Sinai Hospital (2020)
- Postdoctoral Fellowship, University of Toronto, Mount Sinai Hospital (2017)
- PhD, Food process, UMR Nutripass, Institute for research and development (IRD), Université Montpellier II, France (2011)
- MSc, Master of Health, Integrative and molecular biology, French National Research Institute for Agriculture, Food and Environment (INRAE), University of Versailles-Saint-Quentin-en-Yvelines, France (2008)
At a Glance
Dr. Turpin is a microbiologist who is specialized in understanding the role of the human microbiome in health and disease. Currently, he is leading a research program that aims to prevent the onset of chronic immune mediated disease by integrating dietary strategies and multi-omics technologies.
About Dr. Williams Turpin
Dr. Williams Turpin did his undergraduate and graduate work in France where he explored the probiotic and nutritional potential of lactic acid bacteria present in the microbiota of a fermented cereal-based food consumed in Burkina Faso. He pursued his research at the University of Toronto with a focus on understanding the role of human genetic in the composition and function of the gut microbiome. He works closely with clinicians and registered dieticians to apply his research discoveries to real word application. Dr. Turpin is now a translational research scientist at Mount Sinai Hospital. He has research expertise in basic science such as molecular biology, biochemistry, bioinformatic, genomic, germ-free experimentation, cell lines, and culturomics. He is also well versed in translational research including metabolomic, proteomic, immunology, genotyping, statistics, and machine learning. His research program aims to utilize dietary interventions to prevent the onset of inflammatory bowel disease and better understand how nutrition can modulate molecular biomarkers of health and disease. He is especially known for his work related to the GEM project which aims to identify the cause of Crohn’s disease.
Research Synopsis
The Turpin lab is focused on understanding the role of diet in the onset of inflammatory bowel disease, its impact on microbiome and immune response using translational approaches. Thanks to Bayesian statistics and advanced modeling, the Turpin lab is developing personalized dietary recommendation that aims to design menus that are the most efficient in modulating risk associated microbes, gut inflammation, and metabolites at the individual level, potentially preventing the onset of inflammatory bowel disease. In parallel, the Turpin lab also aims to take advantage of observations from human cohorts to test specific hypotheses and potential cures using cell lines, animal models and/ or culturomics to support the development of clinical trials aiming to treat or prevent inflammatory bowel diseases.